THERAPY-RELATED MYELOID-LEUKEMIA

Authors
THIRMAN MJ LARSON RA
Citation
Mj. Thirman et Ra. Larson, THERAPY-RELATED MYELOID-LEUKEMIA, Hematology/oncology clinics of North America, 10(2), 1996, pp. 293
Citations number
140
Categorie Soggetti
Oncology,Hematology
Journal title
Hematology/oncology clinics of North America → ACNP
ISSN journal
08898588
Volume
10
Issue
2
Year of publication
1996
Database
ISI
SICI code
0889-8588(1996)10:2<293:TM>2.0.ZU;2-H
Abstract
One of the most serious possible consequences of cancer therapy is the development of a second cancer, especially leukemia. Several distinct subsets of therapy-related leukemia can be distinguished currently. T hese include classic therapy-related myeloid leukemia, leukemia that f ollows treatment with agents that inhibit topoisomerase II, acute lymp hoblastic leukemia, and leukemias with 21q22 rearrangements or inv(16) or t(15;17). These types of leukemia are discussed in detail in this article.