Kr. Milligan et Dj. Fogarty, THE CHARACTERISTICS OF ANALGESIC REQUIREMENTS FOLLOWING SUBARACHNOID DIAMORPHINE IN PATIENTS UNDERGOING TOTAL HIP-REPLACEMENT, Regional anesthesia, 18(2), 1993, pp. 114-117
Background and Objectives. The postoperative pain scores and analgesic
requirements were assessed in 60 patients who had undergone total hip
replacement under bupivacaine spinal anesthesia. Methods. Thirty of t
he patients had intrathecal diamorphine injected after the bupivacaine
, and the remaining 30 received saline. Results. Superior postoperativ
e pain relief was obtained in the diamorphine group, whose average pos
toperative morphine requirements were t2 +/- 11.4 mg compared to 31 +/
- 18.7 mg (mean +/- SD) in the control group. Despite the lower doses
of morphine, their pain scores over the first 24 hours postoperatively
were consistently lower. No differences were seen between the groups
with respect to respiratory depression, nausea, pruritus, postoperativ
e sedation, headache, or urinary retention. Conclusion. Pain control a
fter intrathecal diamorphine supplemented by intravenous morphine from
a patient controlled analgesia system is superior to intravenous morp
hine alone.