PLASMA N-TAU-METHYLHISTIDINE CONCENTRATION IS A SENSITIVE INDEX OF MYOFIBRILLAR PROTEIN-DEGRADATION DURING STARVATION IN RATS

Authors
NAGASAWA T YOSHIZAWA F NISHIZAWA N
Citation
T. Nagasawa et al., PLASMA N-TAU-METHYLHISTIDINE CONCENTRATION IS A SENSITIVE INDEX OF MYOFIBRILLAR PROTEIN-DEGRADATION DURING STARVATION IN RATS, Bioscience, biotechnology, and biochemistry, 60(3), 1996, pp. 501-502
Citations number
24
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
60
Issue
3
Year of publication
1996
Pages
501 - 502
Database
ISI
SICI code
0916-8451(1996)60:3<501:PNCIAS>2.0.ZU;2-9
Abstract
Urinary excretion of N-tau-methylhistidine (MeHis) in rats was linearl y elevated by starvation for 2 days. Plasma concentration of MeHis on day 1 and day 2 of starvation were increased 2.4- and 2.6-fold, respec tively. The amount of released MeHis from the isolated muscles into me dium during a 2-h incubation period was increased with starvation corr esponded to the plasma MeHis concentration. The results of this study suggest that plasma MeHis is a sensitive index of myofibrillar protein degradation.