I. Berman et al., RISPERIDONE IN ELDERLY SCHIZOPHRENIC-PATIENTS - AN OPEN-LABEL TRIAL, The American journal of geriatric psychiatry, 4(2), 1996, pp. 173-179
The authors assessed the safety and efficacy of risperidone in a group
of elderly, patients with chronic schizophrenia and behavioral distur
bances (N = 10). There were no clinically significant changes on physi
cal examination. Also, schizophrenic symptoms and cognitive performanc
e improved during risperidone administration. Patients showed a suffic
ient improvement in both areas to warrant a larger, double-blind study
assessing the effects of risperidone on cognitive and psychiatric sym
ptoms in elderly psychotic patients.