The CDC National AIDS Hotline provides confidential HIV-related inform
ation and referrals to anonymous callers, twenty-four hours a day. As
part of a continuing quality improvement assessment of caller informat
ional needs, 302 randomly selected anonymous overnight calls to the Ho
tline were evaluated for mental health-related content. Of 302 calls,
34 calls (11.3%) were mental health-related, in that callers spoke abo
ut specific mental health-related topics or requested mental health re
ferrals, and 14 calls (4.6%) included signs or symptoms from the Diagn
ostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-
IV) potentially indicative of mental illness. The results suggest that
training in recognizing and referring mental health calls might be us
eful for Hotline workers. The results also serve as a reminder for all
health care professionals and organizations of the potential for over
lap between patients' mental health-related needs and patients' HIV-re
lated needs.