TREATMENT OF RESISTANT GESTATIONAL CHORIOCARCINOMA WITH TAXOL - A REPORT OF 2 CASES

Authors
JONES WB SCHNEIDER J SHAPIRO F LEWIS JL
Citation
Wb. Jones et al., TREATMENT OF RESISTANT GESTATIONAL CHORIOCARCINOMA WITH TAXOL - A REPORT OF 2 CASES, Gynecologic oncology, 61(1), 1996, pp. 126-130
Citations number
19
Categorie Soggetti
Oncology,"Obsetric & Gynecology
Journal title
Gynecologic oncology → ACNP
ISSN journal
00908258
Volume
61
Issue
1
Year of publication
1996
Pages
126 - 130
Database
ISI
SICI code
0090-8258(1996)61:1<126:TORGCW>2.0.ZU;2-5
Abstract
Two patients with resistant gestational choriocarcinoma were treated w ith Taxol after extensive prior chemotherapy including EMACO and plati num-based salvage chemotherapy. Both patients showed significant respo nses to Taxol. One patient relapsed in the brain and liver after treat ment and died. Taxol was combined with carboplatin in the other patien t who achieved sustained clinical and hormonal remission after craniot omy and excision of resistant disease in the brain. (C) 1996 Academic Press, Inc.