ENANTIOPURE AMINOTRIOL FROM D-ISOASCORBIC ACID SYNTHESIS OF D-THREO-C-18-SPHINGOSINE

Authors
TUCH A SANIERE M LEMERRER Y DEPEZAY JC
Citation
A. Tuch et al., ENANTIOPURE AMINOTRIOL FROM D-ISOASCORBIC ACID SYNTHESIS OF D-THREO-C-18-SPHINGOSINE, Tetrahedron : asymmetry, 7(3), 1996, pp. 897-906
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
7
Issue
3
Year of publication
1996
Pages
897 - 906
Database
ISI
SICI code
0957-4166(1996)7:3<897:EAFDAS>2.0.ZU;2-C
Abstract
Enantiopure suitably N,O-protected aminotriol has been prepared from D -isoascorbic acid. The utility of this homochiral building block in th e synthesis of (2R,3R)-D-threo-C-18-sphingosine is described via a Wit tig reaction on a N,O-protected beta-amino-alpha-hydroxyaldehyde. (C) 1996 Elsevier Science Ltd