THE HORDALAND HOMOCYSTEINE STUDY - THE OPPOSITE TAILS ODDS RATIOS REVEAL DIFFERENTIAL-EFFECTS OF GENDER AND INTAKE OF VITAMIN SUPPLEMENTS AT HIGH AND LOW PLASMA TOTAL HOMOCYSTEINE CONCENTRATIONS

Both female sex and intake of vitamin supplements are known to be asso ciated with a low mean plasma homocysteine level In the present study, we used multiple logistic regression analyses to investigate the rela tion between these two variables and plasma homocysteine at the extrem e ends of the plasma homocysteine distribution curve. We propose that the obtained set of odds ratios for hyper- and hypohomocysteinemia, re ferred to as the opposite tails odds ratios, may be an alternative app roach to study determinants of plasma homocysteine.