Lactobacillus acidophilus is usually considered to be non pathogenic.
We report a case of liver abscess due to Lactobacillus acidophilus in
a 39 year-old man with chronic pancreatitis complicated by both endocr
ine and exocrine insufficiency, and with a choledoco-duodenostomy. Lac
tobacillus acidophilus was isolated in blood and liver samples. Comple
te recovery of the liver abscess occurred after antibiotherapy. We sug
gest that the abnormally low duodenal pH secondary to pancreatic insuf
ficiency may have promoted both Lactobacillus acidophilus adhesion and
multiplication in this patient. The choledoco-duodenostomy may then h
ave promoted biliary tract colonisation.