Lentigo maligna is a pigmented lesion occurring on sun-exposed skin th
at may become lentigo maligna melanoma. The tumor can behave in an agg
ressive fashion, causing significant cosmetic disfigurement, often ext
ending significantly further than the clinical margin. Complete surgic
al excision is the treatment of choice. The authors describe a 74-year
-old woman with a large lentigo maligna of the left cheek, upper and l
ower eyelids, and preauricular skin that had recurred twice. The tumor
was removed using Mohs' micrographic surgery with rush permanent sect
ions and was found to infiltrate extensively the split-thickness skin
graft that had been placed five years earlier. Lentigo maligna can inv
ade and replace a skin graft. Although destructive modalities and conv
entional surgery are recommended by some authors, Mohs' micrographic s
urgery offers the greatest likelihood of cure, the ability to examine
nearly 100 percent of the surgical margins, and maximal tissue sparing
. Complete excision of lentigo maligna at its earliest recognition may
prevent invasive lentigo maligna melanoma and will limit cosmetic dis
figurement.