G. Dubois, CYTOLOGIC SCREENING FOR CERVIX CANCER - EACH YEAR OR EACH 3 YEARS, European journal of obstetrics, gynecology, and reproductive biology, 65(1), 1996, pp. 57-59
Screening is the systematic proposal of a medical procedure to a defin
ed population at a defined interval. The efficacy and effectiveness of
screening can only be demonstrated by a decreased mortality (not leth
ality) in case-control studies or randomised prospective studies. For
cervix cancer, the only test with a decreased mortality proven by case
-control studies (since 1979 only) is the cervix cytologic screening o
r 'Pap' smear. Systematic proposal is proven to be optimal every three
years, no further gain being demonstrated for annual or biennial scre
ening.