NONLINEAR ALIGNMENT AND AVERAGING FOR ESTIMATING THE EVOKED-POTENTIAL

This paper addresses the problems associated with averaging brain resp onses evoked through a repetitive application of an external stimulus, In order to improve the estimate of the evoked potential (EP) through signal averaging, a method which incorporates nonlinear alignment of the EP's into the averaging operation is developed. The method makes n o prior assumptions about the properties of the EP or which response i n the set best characterizes the EP to be estimated, The nonlinear ali gnment procedure is designed to pairwise generate optimally aligned EP 's by backtracking along the optimal alignment path, The nonlinear ali gnment and averaging operations are systematically combined to develop methods to estimate the EP, Results from a series of experiments cond ucted on simulated and real sets of responses show that, through nonli near alignment and averaging, the events in the EP's are preserved and the estimates of the EP are quite robust.