IMMUNOHISTOLOGICAL EVALUATION OF CREUTZFELDT-JAKOB-DISEASE WITH REFERENCE TO THE TYPE PRPRES DEPOSITION

Authors
TATEISHI J KITAMOTO T KRETZSCHMAR H MEHRAEIN P
Citation
J. Tateishi et al., IMMUNOHISTOLOGICAL EVALUATION OF CREUTZFELDT-JAKOB-DISEASE WITH REFERENCE TO THE TYPE PRPRES DEPOSITION, Clinical neuropathology, 15(6), 1996, pp. 358-360
Citations number
8
Categorie Soggetti
Clinical Neurology",Pathology
Journal title
Clinical neuropathology → ACNP
ISSN journal
07225091
Volume
15
Issue
6
Year of publication
1996
Pages
358 - 360
Database
ISI
SICI code
0722-5091(1996)15:6<358:IEOCWR>2.0.ZU;2-Z
Abstract
German patients suspected of having Creutzfeldt-Jakob disease (CJD) an d related diseases were studied pathologically. The immunohistochemica l findings after hydrolytic autoclaving pretreatment sensitively detec ted the synaptic-type deposition of the protease-resistant isoform of the prion protein (PrPres) which thus served to establish the consensu s diagnosis of CJD.