DISAPPEARANCE OF MULTIPLE-SCLEROSIS LESIONS WITH SEVERELY PROLONGED T-1 ON IMAGES OBTAINED BY A FLAIR PULSE SEQUENCE

Although the superiority of FLAIR over conventional T-2-weighted spin- echo (SE) is still unclear, one potential advantage would be its use i n quantitative lesion load measurements, We have observed a potential pitfall regarding the use of FLAIR in image quantification, We report a case where a part of the hyperintense lesions on T-2 SE, which was h ypointense on T-1 SE, subsequently was found to be isointense to brain on FLAIR images, Therefore, quantification of lesion load by means of FLAIR might underestimate the ''true'' lesion load, as seen on T-2 SE .