A NEW METHOD OF BLOOD-SAMPLING AND DETERMINATION OF THE LOCAL-ANESTHETIC AGENT LIDOCAINE IN DENTISTRY

Authors
OERTEL R OERTEL A FELLER K
Citation
R. Oertel et al., A NEW METHOD OF BLOOD-SAMPLING AND DETERMINATION OF THE LOCAL-ANESTHETIC AGENT LIDOCAINE IN DENTISTRY, Methods and findings in experimental and clinical pharmacology, 15(2), 1993, pp. 131-136
Citations number
4
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Methods and findings in experimental and clinical pharmacology → ACNP
ISSN journal
03790355
Volume
15
Issue
2
Year of publication
1993
Pages
131 - 136
Database
ISI
SICI code
0379-0355(1993)15:2<131:ANMOBA>2.0.ZU;2-E
Abstract
Blood levels of local anesthetic agents after application in dentistry have been determined only in peripheral venous blood. A method of wit hdrawing blood from the alveolus after extraction of a tooth was devel oped. With a new simple gas chromatographic method with a low detectio n limit, concentration of lidocaine was determined. A correlation betw een the blood levels of lidocaine and the type of anesthesia and the l ocalization of the extracted teeth was found.