To determine features of the presentation of clinical practice guideli
nes that may enhance their use by internists, we conducted a cross-sec
tional survey to which 1,513 (60%) of 2,513 eligible internists respon
ded, Endorsements by respected colleagues and by major organizations w
ere identified as very important by 72% and 69% of respondents, respec
tively. Respondents preferred short pamphlets and manuals summarizing
a number of guidelines and felt that concise recommendations (86%), sy
nopsis of supporting evidence (85%), and quantification of benefit (77
%) were important in guideline presentation, We conclude that guidelin
e developers should gain the endorsement of major organizations and pr
esent key aspects in brief, easily assimilated formats.