SYNTHESIS, SCREENING AND STRUCTURAL ELUCIDATION OF FLUOROIMINES AND THEIR PT-II COMPLEXES

Fluoro substituted imines ((FN)-N-1 SH) and ((FN)-N-2 SH) have been sy nthesized from thiosemicarbazide and carbonyl compounds, [2-fluorophen yl)methanal] and [1-(2-fluorophenyl)ethanone], respectively. Their met al complexes with the general formulae [Pt((FN)-N-n SH)(2)]Cl-2 and [P t((FN)-N-n S)(2)] have been isolated. A square-planar environment of t he ligands around the metal ion has been suggested on the basis of str uctural units viz., chemical analyses, magnetic measurements, H-1-NMR and electronic spectra, conductance measurements and molecular weight determinations. Fluoroimines and their metal complexes were tested aga inst certain microorganisms to assess their antimicrobial properties a nd the results are indeed positive.