SEPTO-OPTIC DYSPLASIA ASSOCIATED WITH POLYENDOCRINE DYSFUNCTION

Septo-optic dysplasia (SOD) is a rare congenital disease that has been described in association with hypothalamic dysfunction. A case of pol yendocrine dysfunction is described in a 22 year-old white female with septo-optic dysplasia. Findings included atrophic optic nerves, a cav um septum pellucidum and a small pituitary gland detected by magnetic resonance imaging. The patient had central diabetes insipidus, Hashimo to's thyroiditis, and gestational diabetes mellitus. A review of the l iterature is presented. A careful and detailed endocrine evaluation is needed in patients with SOD.