OPTIMIZATION OF SAMPLE PREPARATION TECHNIQUES FOR THE DETERMINATION OF 4-NONYLPHENOL IN WATER AND SEDIMENT

Sample preparation techniques for the determination of 4-nonylphenol i n water and sediments were optimized using two-level orthogonal array design (OAD). Comparison between the use of cartridge-based solid-phas e extraction and membranous disk-based extraction was made for water s amples. For sediment samples, microwave-assisted solvent extraction (M ASE) was employed. A comparison between MASE and classical soxhlet ext raction of spiked samples was also carried out. 4-Nonylphenol was dete rmined using high performance liquid chromatography (HPLC) coupled to both ultraviolet and fluorescence detection.