Non-uniform ion pumping across the bounding membrane of a biological c
ell or artificial vesicle can generate electro-osmotic effects. Self-p
ropulsion of cells at speeds of up to several microns per second is po
ssible. Viscous stresses are generated that lead to significant distor
tion for a membrane lacking considerable reinforcement by, for example
, a cytoskeleton, even if immobilized by adhesion to a substrate. A re
lation between magnitudes of self-induced effects and the measured ele
ctrophoretic mobility is shown. (C) 1996 Academic Press Limited