BRONCHOGENIC CANCER IN THE ELDERLY - OPERATIVE RISK AND LONG-TERM PROGNOSIS

Citation
G. Massard et al., BRONCHOGENIC CANCER IN THE ELDERLY - OPERATIVE RISK AND LONG-TERM PROGNOSIS, The thoracic and cardiovascular surgeon, 44(1), 1996, pp. 40-45
Citations number
17
Categorie Soggetti
Cardiac & Cardiovascular System","Respiratory System",Surgery
ISSN journal
01716425
Volume
44
Issue
1
Year of publication
1996
Pages
40 - 45
Database
ISI
SICI code
0171-6425(1996)44:1<40:BCITE->2.0.ZU;2-P
Abstract
Surgery for bronchogenic cancer raises the question of benefit to elde rly patients. The present study reviews a cohort of 223 patients aged 70 years and more (range: 70-84), who underwent thoracotomy for pulmon ary malignancy over a 10-year period. The aim of the study was to eval uate both operative risk and 5-year survival. Medical history was nega tive in 29% of the patients; 26% had a history of cardio-vascular dise ase, and 19% had a history of malignancy in complete remission. Tumor histology was squamous-cell carcinoma for 70.4%, adenocarcinoma for 24 .2%, large-cell carcinoma for 3.6%, and small-cell carcinoma for 1.3% of the patients. 48.4% of patients were in stage 1, 17.2% in stage II, and 30.3% in stage III. Exploratory thoracotomy was carried out in 5. 8% of patients. A resection was achieved in 210 patients (pneumonectom y in 28.5%, lobectomy in 71.5%). Operative mortality was 7.2% for the whole series, 10% after pneumonectomy and 6.6% after lobectomy. Mortal ity was similar below and above 75 years. Overall 5-year survival was 32.9% (45.7% for stage 1, 36.3% for stage II, and 13.8% for stage III) . Survival was not influenced by age, symptomatic or asymptomatic pres entation, medical history, and in particular not by history of maligna nt disease. Although operative mortality is slightly increased when co mpared to younger patients, longterm results legitimize surgery for br onchogenic cancer in the elderly.