DESIGN, SYNTHESIS AND BIOLOGICAL-ACTIVITY OF NOVEL ENEDIYNYL MONOCYCLIC BETA-LACTAMS

Authors
BASAK A KHAMRAI UK
Citation
A. Basak et Uk. Khamrai, DESIGN, SYNTHESIS AND BIOLOGICAL-ACTIVITY OF NOVEL ENEDIYNYL MONOCYCLIC BETA-LACTAMS, Tetrahedron letters, 37(14), 1996, pp. 2475-2478
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
14
Year of publication
1996
Pages
2475 - 2478
Database
ISI
SICI code
0040-4039(1996)37:14<2475:DSABON>2.0.ZU;2-9
Abstract
Monocyclic beta-lactams 1-3 substituted at C-4 with enediyne moiety ha ve been synthesized via Pd(0) mediated coupling reaction. Their antiba cterial activity against ampicillin-resistant E. coli have been tested . Copyright (C) 1996 Published by Elsevier Science Ltd.