B. Lal et Ak. Gangopadhyay, A PRACTICAL SYNTHESIS OF FREE AND PROTECTED GUANIDINO ACIDS FROM AMINO-ACIDS, Tetrahedron letters, 37(14), 1996, pp. 2483-2486
Synthesis of protected guanidino acids in one pot reaction is achieved
. Amino acids are treated with trimethylsilyl chloride, triethylamine,
dicarbobenzoxy-S-methyl isothiourea in dichloromethone followed by re
movol of silyl group by treatment with methanol to give the correspond
ing carbobenzoxy guanidino acids. Copyright (C) 1996 Elsevier Science
Ltd.