The pharmacologic specificity of low-molecular-weight heparins (LMWHs)
has enabled multiple attractive developments in the prophylaxis and t
reatment of arterial thrombosis. Their high antithrombotic potency ass
ociated with a potentially lower induced bleeding risk, the lack of pl
atelet interaction, the prevention of myointimal hyperplasia, and the
lower incidence of heparin-induced thrombocytopenia, are major advanta
ges. New studies in cardiology and vascular surgery demonstrate a high
efficacy for LMWHs associated with a low risk.