ARE LOW-MOLECULAR-WEIGHT HEPARINS USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF ARTERIAL THROMBI

Citation
Cm. Samama et al., ARE LOW-MOLECULAR-WEIGHT HEPARINS USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF ARTERIAL THROMBI, Haemostasis, 26, 1996, pp. 57-64
Citations number
46
Categorie Soggetti
Hematology
Journal title
ISSN journal
03010147
Volume
26
Year of publication
1996
Supplement
2
Pages
57 - 64
Database
ISI
SICI code
0301-0147(1996)26:<57:ALHUFT>2.0.ZU;2-U
Abstract
The pharmacologic specificity of low-molecular-weight heparins (LMWHs) has enabled multiple attractive developments in the prophylaxis and t reatment of arterial thrombosis. Their high antithrombotic potency ass ociated with a potentially lower induced bleeding risk, the lack of pl atelet interaction, the prevention of myointimal hyperplasia, and the lower incidence of heparin-induced thrombocytopenia, are major advanta ges. New studies in cardiology and vascular surgery demonstrate a high efficacy for LMWHs associated with a low risk.