REACTION OF O-ALKYL-N-SUBSTITUTED IMINOTHIOCARBONATES WITH BROMOACETYL BROMIDE - A GENERAL-METHOD FOR THE SYNTHESIS OF 3-SUBSTITUTED 1,3-THIAZOLIDINE-2,4-DIONES

Authors
IMRICH J BERNAT J KRISTIAN P BUSOVA T HOCOVA S
Citation
J. Imrich et al., REACTION OF O-ALKYL-N-SUBSTITUTED IMINOTHIOCARBONATES WITH BROMOACETYL BROMIDE - A GENERAL-METHOD FOR THE SYNTHESIS OF 3-SUBSTITUTED 1,3-THIAZOLIDINE-2,4-DIONES, Collection of Czechoslovak Chemical Communications, 61(3), 1996, pp. 432-436
Citations number
24
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
61
Issue
3
Year of publication
1996
Pages
432 - 436
Database
ISI
SICI code
0010-0765(1996)61:3<432:ROOIWB>2.0.ZU;2-X
Abstract
Reaction of sodium salts of O-methyl-N-substituted iminothiocarbonates with bromoacetyl bromide represents a new general method for preparat ion of 3-substituted 1,3-thiazolidine-2,4-diones in good yields and hi gh purity. The structure of the synthesized products has been confirme d by H-1 NMR, C-13 NMR, IR and mass spectroscopy as well as by indepen dent synthesis.