CORRELATION BETWEEN THE STRUCTURE AND ACTIVITY OF AMINOSTIGMINE DERIVATIVES CONTAINING VARIOUS SUBSTITUENTS AT THE NITROGEN ATOM OF THE CARBAMOYL GROUP
Vb. Prozorovskii et al., CORRELATION BETWEEN THE STRUCTURE AND ACTIVITY OF AMINOSTIGMINE DERIVATIVES CONTAINING VARIOUS SUBSTITUENTS AT THE NITROGEN ATOM OF THE CARBAMOYL GROUP, Russian journal of applied chemistry, 68(4), 1995, pp. 589-593
Sixteen aminostigmine derivatives containing various substituents at t
he nitrogen atom of the carbamoyl group have been prepared, and their
anticholine esterase activity in vitro, ionization. constants, hydroph
obicity, and toxicity have been determined.