HUMAN ASTROCYTE PRODUCTION OF TUMOR-NECROSIS-FACTOR-ALPHA, INTERLEUKIN-1-BETA, AND INTERLEUKIN-6 FOLLOWING EXPOSURE TO LIPOPOLYSACCHARIDE ENDOTOXIN

Authors
SHARIF SF HARIRI RJ CHANG VA BARIE PS WANG RS GHAJAR JBG
Citation
Sf. Sharif et al., HUMAN ASTROCYTE PRODUCTION OF TUMOR-NECROSIS-FACTOR-ALPHA, INTERLEUKIN-1-BETA, AND INTERLEUKIN-6 FOLLOWING EXPOSURE TO LIPOPOLYSACCHARIDE ENDOTOXIN, Neurological research, 15(2), 1993, pp. 109-112
Citations number
42
Categorie Soggetti
Neurosciences
Journal title
Neurological research → ACNP
ISSN journal
01616412
Volume
15
Issue
2
Year of publication
1993
Pages
109 - 112
Database
ISI
SICI code
0161-6412(1993)15:2<109:HAPOTI>2.0.ZU;2-T
Abstract
The cytokines, tumour necrosis factor (TNF)-alpha, interleukin (IL)-1b eta, and IL-6, have been found in the human central nervous system.. R ecent studies have demonstrated that murine astrocytes produce these c ytokines when induced with lipopolysaccharide endotoxin (LPS). The pre sent study investigates the kinetics of TNF-alpha, IL-1beta, and IL-6 production by normal adult human astrocytes when exposed to LPS.