Mp. Powell et Jr. Spellman, MEDICAL-MANAGEMENT OF THE PATIENT WITH AN ECTOPIC PREGNANCY, The Journal of perinatal & neonatal nursing, 9(4), 1996, pp. 31-43
Ectopic pregnancies are the leading cause of pregnancy-related death d
uring the first trimester. Historically, the treatment for an ectopic
pregnancy was emergency laparotomy, which included salpingectomy. In 1
987, research began at the Regional Medical Center at Memphis, in conj
unction with the University of Tennessee, examining early detection an
d medical treatment for ectopic pregnancy. Pharmacologic management of
an unruptured, size-appropriate ectopic pregnancy is now an establish
ed standard of care. The present protocol recommends single-dose metho
trexate. This form of methotrexate has proven to be a successful, cost
-effective alternative to traditional surgical management of ectopic p
regnancies.