Background: A ''natural language'' measure was developed for classifyi
ng type and severity of communication disturbance in the speech of psy
chotic patients by assessing their linguistic reference performance. M
ethods: This measure was applied to speech samples of schizophrenic, m
anic, and non-psychiatric subjects, and the groups were compared on le
vels and types of communication failures. Results: The speech of the s
chizophrenic and manic subjects contained much higher frequencies of e
ach of six types of communication failures than did the speech of the
control subjects. Proportions of the different types of unclarity diff
ered among the diagnostic groups. Conclusions: This method provides a
measure of overall severity of communication disturbance, discriminate
s the speech of schizophrenic and manic subjects from that of nonpsych
iatric subjects, and reflects some differences in distribution of type
s of communication failure in schizophrenic vs manic patients. The mea
sure may be helpful in elucidating cognitive weaknesses underlying psy
chotic communication failures.