SPINAL LEPTOMENINGEAL DISSEMINATION OF GL IOBLASTOMA

Citation
K. Niklaus et al., SPINAL LEPTOMENINGEAL DISSEMINATION OF GL IOBLASTOMA, Tumordiagnostik & Therapie, 17(1), 1996, pp. 25-29
Citations number
35
Categorie Soggetti
Oncology
Journal title
ISSN journal
0722219X
Volume
17
Issue
1
Year of publication
1996
Pages
25 - 29
Database
ISI
SICI code
0722-219X(1996)17:1<25:SLDOGI>2.0.ZU;2-F
Abstract
Leptomeningeal dissemination is not uncommon in the clinical course of malignant gliomas. We report on a patient who developed spinal sympto ms some months after treatment of a cerebral glioblastoma. On MRI, the re was a thickening and a subarachnoid enhancement of the spinal cord. Pathoanatomically, tumor recurrence and multiple dropping metastases were observed, infiltrating the spinal roots and compressing nerval st ructures. Conclusions: Leptomeningeal metastasis modifies the course o f disease. Diagnosis is facilitated by MRI. Prognosis mostly depends o n the extent of cerebral complications.