DICENTRIC Y-CHROMOSOME WITHOUT EVIDENCE OF MOSAICISM IN AN AZOOSPERMIC MALE

Authors
SASAGAWA I ISHIGOOKA M KATO T HAYAMI S HASHIMOTO F NAKADA T
Citation
I. Sasagawa et al., DICENTRIC Y-CHROMOSOME WITHOUT EVIDENCE OF MOSAICISM IN AN AZOOSPERMIC MALE, Scandinavian journal of urology and nephrology, 30(1), 1996, pp. 75-76
Citations number
12
Categorie Soggetti
Urology & Nephrology
Journal title
Scandinavian journal of urology and nephrology → ACNP
ISSN journal
00365599
Volume
30
Issue
1
Year of publication
1996
Pages
75 - 76
Database
ISI
SICI code
0036-5599(1996)30:1<75:DYWEOM>2.0.ZU;2-6
Abstract
A phenotypically male of dicentric Y chromosome with no evidence of se x chromosomal. mosaicism is reported. Staining of fluorescence in situ hybridization using Y chromosome centromere-specific DNA probe showed the presence of two bright fluorescent spots in Y chromosome. Testicu lar histology revealed maturation arrest at the stage of primary sperm atocyte. It is suggested that structural anomaly of the Y chromosome i s related to the disturbance of spermatogenesis.