LITHIATIONS DIRECTED BY CARBOXYLIC-ACID, FLUORINE AND CHLORINE - THE REGIOSELECTIVE SYNTHESIS OF POLYSUBSTITUTED BENZOIC-ACIDS AND ACETOPHENONES

Authors
MOYROUD J GUESNET JL BENNETAU B MORTIER J
Citation
J. Moyroud et al., LITHIATIONS DIRECTED BY CARBOXYLIC-ACID, FLUORINE AND CHLORINE - THE REGIOSELECTIVE SYNTHESIS OF POLYSUBSTITUTED BENZOIC-ACIDS AND ACETOPHENONES, Bulletin de la Societe chimique de France, 133(2), 1996, pp. 133-141
Citations number
36
Categorie Soggetti
Chemistry Inorganic & Nuclear",Biology,Chemistry
Journal title
Bulletin de la Societe chimique de France → ACNP
ISSN journal
00378968
Volume
133
Issue
2
Year of publication
1996
Pages
133 - 141
Database
ISI
SICI code
0037-8968(1996)133:2<133:LDBCFA>2.0.ZU;2-K
Abstract
Lithiations directed by carboxylic acid, fluorine and chlorine: the re gioselective synthesis of polysubstituted benzoic acids and acetopheno nes. Lithiation/electrophilic quenching of ortho-lithiated benzoates a llows the totally regiocontrolled synthesis of a wide range of 2,3-, 2 ,3,4-, and 2,3,4,5-polysubstituted benzoic acids and related acetophen ones.