SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NEW ARYLIDENEHYDRAZIDESAND 4-THIAZOLIDINONES

Authors
ULUSOY N ERGENC N EKINCI AC OZER H
Citation
N. Ulusoy et al., SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NEW ARYLIDENEHYDRAZIDESAND 4-THIAZOLIDINONES, Monatshefte fuer Chemie, 127(11), 1996, pp. 1197-1202
Citations number
14
Categorie Soggetti
Chemistry
Journal title
Monatshefte fuer Chemie → ACNP
ISSN journal
00269247
Volume
127
Issue
11
Year of publication
1996
Pages
1197 - 1202
Database
ISI
SICI code
0026-9247(1996)127:11<1197:SAAAOS>2.0.ZU;2-2
Abstract
A number of N,N'-bis(arylidene)mono(1-methylpropyl)malonic acid dihydr azides (3a-c), hiazolidinone-3-yl)amino]carbonyl]-2-methylbutanes (4a- e), and olidinone-2-yl)hydrazono]carbonyl]-2-methylbutanes (6a-i) have been synthesized, characterized and evaluated for anticonvulsant acti vity. All tested compounds showed significant activity (10 to 60% prot ection) against pentylenetetrazole induced seizures.