The sponge Astrosclera willeyana contains seven new bromopyrrole alkal
oids (3-9), together with the known alkaloids bromoageliferin (10) aci
d dibromoageliferin (11). The structures of the new alkaloids (3-9), a
geliferins that are methylated on one or both of the pyrrole nitrogens
, were elucidated by interpretation of spectral data. Chemotaxonomic r
elationships involving bromopyrrole alkaloids are discussed in the lig
ht of this research. Copyright (C) 1996 Elsevier Science Ltd