A new algorithm, based on Tikhonov regularization with a differential
operator, is proposed for image reconstruction from projection data. T
he algorithm reconstructs the smoothest image amongst all possible ima
ges yielding a given fit to the data. In addition, the algorithm compu
tes measures of the spatial resolution and variance of the constructed
image, which characterize its non-uniqueness due to incomplete data c
overage and noise in the data. Under the assumption of straight raypat
hs and a circular imaging region, we derive analytical expressions for
the reconstructed image and resolution/variance measures. For a fixed
data acquisition geometry and fixed noise statistics, the reconstruct
ion is linear in the data and the non-uniqueness measures are independ
ent of the data, suggesting the possibility of applying a precomputed
inversion operator to new data sets to achieve real-time image constru
ction. Numerical examples show that the new technique works at least a
s well as the algebraic reconstruction technique (ART) and is stable a
gainst strong noise in the data.