CURRENT CONCEPTS AND CASE-REPORT OF NEONA TAL HERPETIC ENCEPHALITIS

We describe a newborn patient with herpes simplex infection localized to the central nervous system. The diagnosis was suspected on clinical grounds and it was corroborated by tissue culture isolation of the vi rus and by herpes simplex glycoprotein B DNA detection by PCR in cereb rospinal fluid. We describe the clinical manifestations of this patien t and we present some considerations regarding pathogenesis, diagnosis , prognosis and treatment of this viral infection in the newborn perio d.