Perceived changes in occlusion and decreased range of motion are often
expressed by patients with masticatory muscle pain. The adverse loadi
ng of craniomandibular tissues that results from an inadequate maxillo
mandibular relationship in combination with the coexisting dysfunction
is widely regarded as the cause of pain. This study was designed to t
est whether pain can cause significant changes in position of the mand
ible and therefore form the basis for any perceived changes in the max
illomandibular relationship. A second objective was to determine wheth
er pain can cause changes in the mandibular range of motion. Five subj
ects who rated pain intensity on a visual analog scale were used in a
single-blind, randomized, repeated-measures study design. Tonic muscle
pain was induced by infusion of 5% hypertonic saline solution into th
e central portion of the superficial masseter muscle. Isotonic saline
solution was used as a control, with subjects blinded to the type of s
ubstance given. The effect of pain on the position of the apex of the
gothic arch tracing, the direction of the lateral mandibular border mo
vements, and the mandibular range of motion was studied in a horizonta
l plane with minimal. occlusal separation. Pain significantly affected
the position of the apex of the gothic arch tracing in anterior (F =
11.46, p = 0.03) and transverse (F = 35.0, p = 0.004) directions. Simi
larly, pain affected the orientation of the mandibular lateral border
movements (F = 12.44, p = 0.02) and their magnitude (F = 14.97, p = 0.
01). All pain-induced effects proved to be reversible. The observed ef
fect of pain can explain the perceived change of bite that is frequent
ly noted by patients with orofacial pain. This study provided evidence
of an alternative causal relationship between pain and changes in occ
lusal relationship and questions occlusal therapy as treatment, direct
ed toward the elimination of the underlying cause in patients with mas
ticatory muscle pain.