Ae. Yucel et al., FALSE-POSITIVE PLEURAL BIOPSY AND HIGH CA125 LEVELS IN SERUM AND PLEURAL EFFUSION IN SYSTEMIC LUPUS-ERYTHEMATOSUS, Clinical rheumatology, 15(2), 1996, pp. 197-199
A 23-year-old female with systemic lupus erythematosus is reported. Th
e clinical features included fever, shortness of breath, lymphadenopat
hies, hepatosplenomegaly, pleural and pericardial fluids, ANA and Anti
-DNA positivity. Pleural biopsy was false positive for malignancy on t
wo occasions. High CA125 levels were detected in both serum and pleura
l fluid. Following prednisolone treatment, clinical and laboratory fin
dings returned to normal.