PRADIMICIN-T1 AND PRADIMICIN-T2, NEW ANTIFUNGAL ANTIBIOTICS PRODUCED BY AN ACTINOMYCETE .1. TAXONOMY, PRODUCTION, ISOLATION, PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES

Authors
FURUMAI T HASEGAWA T KAKUSHIMA M SUZUKI K YAMAMOTO H YAMAMOTO S HIRANO M OKI T
Citation
T. Furumai et al., PRADIMICIN-T1 AND PRADIMICIN-T2, NEW ANTIFUNGAL ANTIBIOTICS PRODUCED BY AN ACTINOMYCETE .1. TAXONOMY, PRODUCTION, ISOLATION, PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES, Journal of antibiotics, 46(4), 1993, pp. 589-597
Citations number
39
Categorie Soggetti
Pharmacology & Pharmacy",Immunology
Journal title
Journal of antibiotics → ACNP
ISSN journal
00218820
Volume
46
Issue
4
Year of publication
1993
Pages
589 - 597
Database
ISI
SICI code
0021-8820(1993)46:4<589:PAPNAA>2.0.ZU;2-N
Abstract
Pradimicins T1 and T2, new members of the pradimicin family of antibio tics, were produced by an actinomycete strain AA3798. Pradimicin TI ex hibited potent activity against a wide spectrum of fungi in vitro. and demonstrated efficacy against systemic Candida albicans and Aspergill us fumigatus infections in mice.