A 3-year-old male with steroid-responsive nephrotic syndrome developed
a rare complication, sagittal sinus thrombosis during an episode of g
astroenteritis, while on steroid therapy. Anticoagulation, as assessed
by partial thromboplastin time, was difficult to maintain, despite ad
ministering high doses of heparin, infusions of fresh-frozen plasma to
provide antithrombin III, and, subsequently, maximum doses of warfari
n (0.3 mg/kg per day). Despite these problems the child made a complet
e neurological recovery.