We evaluated the effects of plasmapheresis in two patients with Morvan
's fibrillary chorea, one of whom had sigmoid carcinoma, with oligoclo
nal bands in the cerebrospinal fluid, and modifications of the lipid-o
xidative muscle pattern. The use of plasmapheresis in the treatment of
Morvan's fibrillary chorea has not been reported previously and in ou
r patients improved the symptoms markedly.