Gt. John et al., GASTRIC ASPIRATION FOR DIAGNOSIS OF PULMONARY TUBERCULOSIS IN ADULT RENAL-ALLOGRAFT RECIPIENTS, Transplantation, 61(6), 1996, pp. 972-973
Of 213 renal allgroft recipients suspected to have had pulmonary tuber
culosis, 132 had sputum examinations and 14 showed acid-fast bacilli.
Of the remaining 118 patients, 25 had gastric aspirations, 18 had bron
choalveolar lavage, and 75 did not require further investigation becau
se of spontaneous improvement or confirmation of an alternative diagno
sis. While 9 of the 25 patients' gastric aspirate examination was posi
tive, all the 18 who had bronchoalveolar lavage were negative for acid
-fast bacilli. Eighty-one patients without expectoration had gastric a
spiration directly and 14 showed acid-fast bacilli. Of the remaining 6
7 patients only 17 had bronchoalveolar lavage, of which three were pos
itive for AFB and the rest did not require further testing for tubercu
losis. A total of 106 patients had gastric aspiration, Acid-fast bacil
lus positivity was significantly more (P<.01) in patients with abnorma
l chest radiographs as compared with patients with normal chest radiog
raph results. We suggest gastric aspiration for AFB in all renal trans
plant recipients who have fever, scanty expectoration, and abnormal ch
est radiograph with clinical suspicion of pulmonary tuberculosis.