SACCHAROMYCES-CEREVISIAE TEC1 IS REQUIRED FOR PSEUDOHYPHAL GROWTH

Diverse eukaryotic organisms share developmental transcription factors with homologous DNA-binding domains. We showed that the developmental regulator AbaA, a member of the ATTS/TEA ((A) under bar b(a)A, (T) un der bar EF-1, (T) under bar EC1, Scalloped/(T) under bar EF-1, (T) und er bar EC1, (A) under bar baA) class of transcription factors of the f ilamentous fungus Aspergillus nidulans, induces pseudohyphal developme nt in the yeast Saccharomyces cerevisiae. The S. cerevisiae homologue of AbaA, TEC1p, is required for this morphological transition. We prov ide evidence that TEC1p functions in co-operation with STE12p to induc e pseudohyphal development.