DETERMINATION OF THE PRESENCE OF A DIASTEREOMERIC IMPURITY WITHIN A SYNTHETIC PEPTIDE BY COMBINED LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY TECHNIQUES

Authors
RAMSEY ED LAWRENCE SD GAMES DE HEWLINS MJE MCDOWALL MA
Citation
Ed. Ramsey et al., DETERMINATION OF THE PRESENCE OF A DIASTEREOMERIC IMPURITY WITHIN A SYNTHETIC PEPTIDE BY COMBINED LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY TECHNIQUES, Analytical communications, 33(2), 1996, pp. 79-83
Citations number
27
Categorie Soggetti
Chemistry Analytical
Journal title
Analytical communications → ACNP
ISSN journal
13597337
Volume
33
Issue
2
Year of publication
1996
Pages
79 - 83
Database
ISI
SICI code
1359-7337(1996)33:2<79:DOTPOA>2.0.ZU;2-R
Abstract
The use of two different LC-MS techniques, using moving-belt and conti nuous-flow FAB, has provided complementary means of determining the pr esence of a diastereomeric impurity within a protected tripeptide phar maceutical precursor.