L. Ersoy et al., DETERMINATION OF POLY(ETHYLENE GLYCOL)-400 IN URINE BY FOURIER TRANSFORM-INFRARED SPECTROMETRY, Analytical communications, 33(1), 1996, pp. 19-20
A simple and rapid method for the analysis of poly(ethylene glycol)-40
0 (PEG-400) (used in the study of intestinal physiology) in human urin
e is described using Fourier transform-infrared spectrometry, The quan
titative measurements were carried out by using the absorbance value o
f the C-O-C band (wavenumber 1100 cm(-1)). The lower limit of determin
ation of PEG-400 in human urine was 0.8 mg cm(-3), Analytical recovery
of PEG-400 added to urine controls was 99.6%, The results of the anal
yses of one urine sample were compared with those obtained by using hi
gh-performance liquid chromatography. Limitations and advantages of th
e two systems are discussed.