U. Joos et al., STRIP OSTECTOMY AND RADICAL OSTECTOMY IN THE TREATMENT OF CRANIOSYNOSTOSIS - AN EXPERIMENTAL ANIMAL STUDY, Journal of cranio-maxillo-facial surgery, 21(3), 1993, pp. 89-92
In an experimental animal study using rabbits, growth phenomena were s
imulated which are comparable to craniosynostosis in humans. The radio
logical and histological findings after surgical management of these a
rtificial craniosynostoses by means of strip ostectomy or radical oste
ctomy were compared with the findings obtained in control animals. Fol
lowing strip ostectomy, bone defects were rapidly filled by the format
ion of suture-like structures. After radical ostectomy, structures con
sisting of connective tissue dispersed among islands of ossification w
ere preserved over a considerable period of time, making it possible f
or the calvarium to adapt to the fast-growing brain. In contrast to st
rip ostectomy, after radical ostectomy growth of both the neurocranium
and the viscerocranium, as well as the total sagittal growth of the s
kull, were almost identical to the corresponding growth in the control
animals.