A NEW AND EFFICIENT CONVERSION OF ALKYLPHENOLS INTO THE CORRESPONDINGSUBSTITUTED SALICYLIC ACIDS

Authors
KATRITZKY AR LANG HY LAN XF
Citation
Ar. Katritzky et al., A NEW AND EFFICIENT CONVERSION OF ALKYLPHENOLS INTO THE CORRESPONDINGSUBSTITUTED SALICYLIC ACIDS, Synthetic communications, 23(8), 1993, pp. 1175-1182
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
23
Issue
8
Year of publication
1993
Pages
1175 - 1182
Database
ISI
SICI code
0039-7911(1993)23:8<1175:ANAECO>2.0.ZU;2-I
Abstract
A three-step sequence suitable for the synthesis of alkyl substituted salicylic acids from the corresponding alkylphenols involves ortho-dir ected lithiation of the methoxymethyl aryl ethers followed by quenchin g with carbon dioxide and deprotection under acidic conditions.