MONOAMINE METABOLISM IN DIFFERENT FORMS O F PARAPHILIA

42 persons which commited crime sexual actions were examined in terms of clinical and neurochemical investigations. The sexual behaviours of 31 patients from this group were associated with sexual inclination p athology - with paraphilla. The patients were divided into 2 groups na mely with compulsive form of paraphilia (13 individuals) and without c ompulsive disturbances (18 patients). Both free and conjugated forms o f norepinephrine (NA), dopamine (DA), dihyroxyphenylalanine (DOPA) and dihyroxyphenylacetic acid (DOPAC) were measured in serum and daily ur ine as well as serotonin concentration was estimated in blood plasma a nd platelets. The rate of H-3-serotonin uptake into platelets (Vmax) w as also investigated. It was determined that Vmax, free and especially conjugated forms of NA, DA, DOPAC levels were significantly higher in patients with compulsive forms of paraphilia. it was supposed that mo noamine mechanisms may be operated in psychopathological variations of the crime sexual behaviour.