E. Mohr, WHAT IS THE MEANING OF ]]NORMAL[[ - A COM MENTARY ON THE NORMAL RANGES OF CLINICAL-PATHOLOGICAL DIAGNOSTIC PARAMETERS FOR SHEEP, Tierarztliche Umschau, 51(4), 1996, pp. 229-232
Diagnostic mis-interpretations may occur when the state of health of a
n animal is determined when only the clinical standard of a physiologi
cal parameter is used. Ir is important to remember that such standards
are prone to the normal statistical variation, and from the published
literature, in some cases this is quite large. The objective of the p
resent study was to provide some clarification of this problem using a
prospective approach. Physiological functions of domestic animals wer
e found to be the result of continuous rhythmic variations, suggesting
that homeodynamic is a better term than homeostasis. Modifications of
this dynamic process may appear before the onset of clinical signs of
a systemic disturbance, indicating that the homeodynamic is a very se
nsitive measurement. Validation of the homeodynamic, using non-linear
dynamic methodology, provides a means of determining the health status
of an animal using only one variable.