INTERACTION OF ANTIBIOTIC AND G-CSF IN PO STOPERATIVE PERITONITIS

Authors
REIMUND KP CELIK I BAUHOFER A GREGER B ROTHMUND M LORENZ W
Citation
Kp. Reimund et al., INTERACTION OF ANTIBIOTIC AND G-CSF IN PO STOPERATIVE PERITONITIS, Langenbecks Archiv fur Chirurgie, 1996, pp. 7-10
Citations number
6
Categorie Soggetti
Surgery
Journal title
Langenbecks Archiv fur Chirurgie → ACNP
ISSN journal
00238236
Year of publication
1996
Supplement
1
Pages
7 - 10
Database
ISI
SICI code
0023-8236(1996):<7:IOAAGI>2.0.ZU;2-S
Abstract
Several clinically relevant antibiotics produce various interactions w ith G-CSF. These interactions of cytokines and antibiotics explain fai lures in clinical trials on sepsis. However they demand strongly trial groups that analyse these interactions before using G-CSF and other c ytokines in sepsis trials. In addition they emphasize again the import ance of a clinically relevant animal model.